Researchers have developed an innovative mRNA therapy that targets the root cause of preeclampsia. The breakthrough treatment could improve health outcomes for the up to 8 percent of mothers affected worldwide.
is a condition that affects between 3-8 percent of pregnancies worldwide and can lead to stillbirths and premature birth. It is caused by high maternal blood pressure and restricted blood flow from the mother to the fetus.
However, Penn engineers have made a breakthrough in reproductive health care by developing targeted RNA therapy to treat preeclampsia. According to a new study published in the, scientists have successfully delivered mRNA to placental cells to create vascular endothelial growth factor , a protein that helps expand the blood vessels in the placenta to reduce maternal blood pressure and restore adequate circulation to the fetus.
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