A new tool that can reveal a key pathology of Parkinson's disease in brain and body cells has been discovered after lab testing to confirm the presence of the biomarker.
Charles Shields, who has Parkinson's disease and is in hospice, says it's a miracle he was able to walk for the first time after being bedridden for several years.a key pathology of Parkinson's diseaseThe identification of the new biomarker, known as abnormal alpha-synuclein, opens a new chapter for research, according to The Michael J. Fox Foundation for Parkinson's Research.
The foundation led the coalition and its landmark clinical study, Parkinson’s Progression Markers Initiative .Michael J. Fox poses backstage at the 52nd Emmy Awards at the Shrine Auditorium in Los Angeles on Sept. 10, 2000. The tool, also known as the α-synuclein seeding amplification assay, is able to detect pathology in spinal fluid both for those diagnosed with the disease and individuals who are at high risk of developing it but have not yet been diagnosed or exhibited clinical symptoms.
The laboratory testing can confirm the presence of abnormal alpha-synuclein, which is detected in most people who have Parkinson's with what the foundation said was"astonishing accuracy." Fox attends the 2023 Sundance Film Festival premiere of"Still: A Michael J. Fox Movie" at Eccles Center Theater in Park City, Utah, on Jan. 20, 2023.
"We've never previously been able to see in a living person whether they have this alpha-synuclein biological change happening in their body," Dr. Todd Sherer, chief mission officer at
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