Super-agers: what are their brain secrets?
The study focused on what scientists have dubbed "super-agers" — a select group of elderly adults who have the memory skills of people decades younger.
The researchers found that in a memory-related area of the brain, super-agers had larger neurons than elderly adults with average brain power — and even in comparison to people 30 years their junior.Alzheimer'sTau is a protein that, in healthy brain cells, helps stabilize the internal scaffolding. But abnormal versions of tau — ones that cling to other tau proteins — can develop as well.
Researchers at Northwestern University, in Chicago, have been studying super-agers for years. In previous work the investigators found that those unusually sharp seniors are similar to their cognitively average peers when it comes to amyloid plaques: Both groups have comparable amounts in their brains.
Where they differ is in tau buildup. Super-agers have far fewer tau tangles in a memory-related area of the brain called the entorhinal cortex.adds to that picture. Super-agers also have larger neurons in the entorhinal cortex.
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