What octopus and human brains have in common ScienceAdvances
"So this is what connects us to the octopus," says Professor Nikolaus Rajewsky, scientific director of the Berlin Institute for Medical Systems Biology of the Max Delbrück Center , head of the Systems Biology of Gene Regulatory Elements Lab, and the paper's last author. He explains that this finding probably means miRNAs play a fundamental role in the development of complex brains.
The results of the analyses were surprising:"There was indeed a lot of RNA editing going on, but not in areas that we believe to be of interest," says Rajewsky. The most interesting discovery was in fact the dramatic expansion of a well-known group of RNA genes, microRNAs. Rajewsky has been researching miRNAs for more than 20 years. Instead of being translated into messenger RNAs, which deliver the instructions for protein production in the cell, these genes encode small pieces of RNA that bind to messenger RNA and thus influence protein production. These binding sites were also conserved throughout cephalopod evolution—another indication that these novel miRNAs are of functional importance.
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Astronomers trace 84 bright blasts to colliding stars in ancient galaxiesRobert Lea is a science journalist in the U.K. whose articles have been published in Physics World, New Scientist, Astronomy Magazine, All About Space, Newsweek and ZME Science. He also writes about science communication for Elsevier and the European Journal of Physics. Rob holds a bachelor of science degree in physics and astronomy from the U.K.’s Open University. Follow him on Twitter sciencef1rst.
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