For the first time, scientists have created a hybrid of the two seasonal viruses. Their discovery yielded a few surprises
have confirmed that RSV and influenza compete against each other to infect a cell and multiply. This competition makes the chance of a hybrid forming in nature even more unlikely. But not impossible.To create the right conditions for two unrelated viruses to meet, scientists in the U.K. infected human lung cells in a dish in the laboratory with both influenza A and RSV viruses.
The hybrid viruses were capable of infecting lower respiratory tract cells, not typically targeted by the flu virus. The hybrid virus was able to dodge flu antibodies, but antibodies against RSV effectively stopped the hybrid’s spread. Most people already have antibodies against RSV and flu after infections during their toddler years. So a hybrid virus between RSV and flu is unlikely to pose a threat by generating an immune escaping virus. Rather it is just like two viruses packaged in a single envelope, says Murcia.
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