Single-cell suspension may be the missing ingredient in lab-grown beef.
, there are plenty of alternatives options. Substitutes like tofu patties don’t always seem to perfectly scratch that itch for meat-lovers.
“This is a challenge because, as you know, mammalian cell culture is super expensive,” says Kasia Gora, synthetic biologist and co-founder of. Currently, biopharma companies are the primarily large-scale lab developers of mammalian cells, explains Gora. This cell line research has been important in early stage pharmaceutical development, but the processes are expensive. “It works and it’s fantastic if you can charge $1,000,000 a gram for your product,” Gora says. “But food has to be cheap.
To combat this, typically companies will use tiny beads for the cells to glom on to, but as the cell masses accumulate this can become bulky and bump or damage other growing cell beads, Specht adds. Her team has found that a more effective approach is growing in single-cell suspension, or when cells just grow floating around on their own like yeast in a brewery vessel. Without the beads or any surface at all, costs go down and efficiency goes up.
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