A local scientific discovery may soon breathe new life into patients starved of oxygen.
In a new study published in PNAS, investigators at Harrington Discovery Institute and Case Western Reserve School of Medicine showed that a modified version of hemoglobin, termed S-nitrosohemoglobin, senses areas with insufficient oxygen, and then restores blood flow for oxygenation CLEVELAND, Ohio —
In these cases, the problem isn’t the availability of oxygen. Instead, it’s that increasing oxygen levels in the blood doesn’t translate into similar increases in oxygen delivery to the places where it’s needed. However, Stamler and his colleagues at Harrington Discovery Institute at University Hospitals and Case Western Reserve University School of Medicine have recently demonstrated that they can restore blood flow and oxygenate tissues using a modified version of the oxygen carrying molecule hemoglobin.
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