Photodynamic diagnosis-guided TURBT did not reduce 3-year recurrence rates of non–muscle-invasive bladdercancer in a real-world trial compared with white light-guided cystoscopy. EAU2023
MILAN — Photodynamic diagnosis-guided transurethral resection of bladder tumors did not reduce recurrence rates of non–muscle-invasive bladder cancer in the longer term compared with standard white light cystoscopy, according to a recent randomized trial conducted in the UK.
Recurrences occurred in 86 patients in the PDD group and 84 patients in the WL group . The 3-year recurrence rates were similar — 57.8% in the PDD group and 61.6% in the WL group . Invited discussant Morgan Rouprêt, MD, PhD, from Pitié-Salpêtrière Hospital in Paris, expressed skepticism about the study findings, given previous trials demonstrating strong evidence for the benefits of photodynamic diagnosis.
In a rebuttal, Heer explained that the trial had a pragmatic design and was conducted in a real-world setting.
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