Most are already commercially available for other indications.
to produce significant improvement in both symptom burden and heart rate response in POTS.
“We suggest that treatable neurovascular dysregulation underlies acute exercise intolerance in ME/CFS. … Pyridostigmine may be a useful repurposed off-label treatment [for] a subset of patients with exercise intolerance,” Systrom said. on use of the commercially available nutritional supplement anhydrous enol-oxaloacetate for treating mental and physical fatigue in 76 patients with longstanding ME/CFS and 43 with long-COVID fatigue.depleted in patients
The only adverse effects were occasional dyspepsia, which was avoided by taking the supplement with food, and insomnia, resolved by having them dose at breakfast and lunch, Kaufman said.clinical trial “It's a benign drug, and it's over the counter. I would give it to any patient who's got a big wallet,” Lapp quipped, adding, “If they've got the money, they can order it tonight.”Inspiritol is an investigational"nebulized, inhaled, multi-mechanism medication designed to treat the major symptoms of respiratory distress with antioxidant, anti-inflammatory, and broad spectrum antiviral and antibacterial properties.
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