Researchers have designed proteins that self-assemble into tiny machine parts for use in molecular engines
bacteria, and then checked their structure using a method called cryogenic electron microscopy.inside the rotors, and also revealed the different conformations that would be expected if the axles were turning in the rotors. But because cryogenic electron microscopy can only provide a series of stills rather than a moving picture, the team cannot say for sure if the axles are turning in the rotors.– molecules knocking into each other as they move around.
“I am very impressed with the structural detail with which the Baker group has built this protein rotary assembly,” says at Technical University of Munich in Germany. “I will be waiting eagerly to see how the group will implement an energy input to the system to drive the motion in one direction.”, and two other groups have also created moving machines made of DNA, he says. “I will say, though, that the de novo protein design field is catching up rapidly and might overtake the DNA field soon.
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