We often experience forgetting as a frustration, or a glitch in the memory system. But new research shows it has real value.
baby zebrafish is just half the size of a pea. A recent look inside its transparent brain, however, offers clues to the far bigger mystery of how we remember—and how we forget.
Image showing synaptic changes when a memory is made. Each yellow dot represents a new synaptic connection formed; each blue dot represents a connection lost.This glimpse into the mind of a zebrafish illuminates one of the most intriguing new fronts in science’s quest to understand the brain: the biology of forgetting.
The brain forms memory with the help of a complex tool kit of neurotransmitters, proteins, and carbohydrates, as well as other cells, Small writes; forgetting, too, has its own set of dedicated molecular tools working to clear away what’s no longer relevant. The Nobel Prize–winning neuroscientist Eric Kandel, a professor of biochemistry and biophysics at Columbia University, established in the 1970s that changes in the chemical signals between neurons wereWhen neighboring brain cells, or neurons, are excited at the same time, neurotransmitter chemicals fire across the microscopic gap between the ends of the neurons’ spindly dendrites. This change in the synapse—the connection point—between neurons is what makes a memory.
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