To raise awareness for breastcancer awareness month, here is a translational study on the role of androgen receptor as a tumorsuppressor in estrogen receptor-positive breast cancer breastcancerawareness Notimetowaste
gene locus as depicted in . Bar graphs depict mean ± SEM of 3 independent passages of cells. Data was analyzed using a one-sided unpaired t-test. ER ChIP;= 1.345, 1.17, and 0.5662 for Enh. 1 , Intron 1 , AR status , and their interaction , respectively; where ****p < 0.0001. Lower-right panel;= 0.1975, 147.1, and 0.09898 for presence of E2 , AR status , and their interaction , respectively; where ****p < 0.0001.
df=4 for each test. Bar graphs depict mean ± SEM of 3 independent passages of cells. NS = Not significant; **p < 0.01; ****p < 0.0001.Growth curve showing that induction of constitutively-active AR inhibits E2-stimulated growth but induction of the constitutively-active ARdoes not. Data represents mean ± SD of three replicate cell culture wells per condition, and is a representative of two independent experiments.