An analysis of more than 400 brain scans has revealed a potential new biomarker for depression.
Having a smoother brain surface could reveal your likelihood of developing major depressive disorder , according to a new study.
The answer may lie in looking at the ratio of curved to smooth surfaces of the cortex, using a measurement called the Local Gyrification Index , the researchers behind the new study propose.By analyzing more than 400 brain scans from individuals with MDD and comparing them to scans from people without the condition, the scientists found that the former individuals have comparatively fewer folds in several key regions of the cortex, meaning those portions of the cortex look"smoother.
The team measured the degree of folding in 66 regions of the cortex using LGI. A higher LGI corresponds to a surface that is more folded, and vice-versa.
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