It includes the largest ever federal effort on climate change - close to $400 billion - hands Medicare the power to negotiate pharmaceutical prices and extends expiring subsidies that help 13 million people afford health insurance.
Biden's original measure collapsed after conservative Sen. Joe Manchin, D-W.Va., opposed it, saying it was too costly and would fuel inflation.
One GOP proposal would have forced the Biden administration to continue Trump-era restrictions that cited the pandemic for reducing the flow of migrants across the Southwest border. Before debate began Saturday, the bill's prescription drug price curbs were diluted by the Senate's nonpartisan parliamentarian. Elizabeth MacDonough, who referees questions about the chamber's procedures, said a provision should fall that would impose costly penalties on drug makers whose price increases for private insurers exceed inflation.
Sinema forced Democrats to drop a plan to prevent wealthy hedge fund managers from paying less than individual income tax rates for their earnings. She also joined with other Western senators to win $4 billion to combat the region's drought.
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