Scientists develop novel circulating tumorDNA biosensor acsnano
Miao Peng's group from the Suzhou Institute of Biomedical Engineering and Technology of the Chinese Academy of Sciences has recently developed an electrochemical DNA nanomachine based on looped bipedal DNA walking reaction for highly sensitive analysis of nucleic acids.
Furthermore, they developed a novel looped bipedal DNA walking strategy. The two loops of dumbbell structured DNA probe contained DNAzyme sequences, which could not react with the track strands at the electrode interface initially .
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