Analyses of data from more than 200,000 individuals identify phenotypic features associated with carrying variants in autism-associated genes, in individuals with and without a diagnosis of autism ThomasRolland75 ThomasBourgeron GHFC_lab
We performed ordinal logistic regression analyses for autism status using the below formula. The same formula was used for autism status and cognitive impairment in the iPSYCH replication sample.
We performed linear regression analyses for fluid intelligence score and Townsend deprivation index on UK Biobank individuals using the following formula: $$\begin{array}{rcl}{\mathrm{Response}} & \sim & {{{\beta}}}_{1}{\mathrm{LoF}}+{{{\beta}}}_{2}{\mathrm{PGS}}+{{{\beta}}}_{3}{\mathrm{sex}}+{{{\beta}}}_{4}{\mathrm{LoF}}\times {\mathrm{PGS}}\\&&+\,{{{\beta}}}_{6}{\mathrm{age}}+{{{\beta}}}_{7}{\mathrm{PC}}1+{{{\beta}}}_{8}{\mathrm{PC}}2+{{{\beta}}}_{9}{\mathrm{PC}}3+{{{\beta}}}_{10}{\mathrm{PC}}4+\varepsilon\end{array}$$
Multivariable linear regressions were performed separately for each 68 cortical regions and 16 subcortical regions using the following formula, adding the total measure for each metric as a covariate: $$\begin{array}{rcl}{\rm{Response}} & \sim & {\beta}_{0}+{\beta}_{1}{\rm{LoF}}+{\beta}_{2}{\rm{PGS}}+{\beta}_{3}{\rm{sex}}+{\beta}_{4}{\rm{age}}+{\beta}_{5}{\rm{LoF}}:{\rm{PGS}}\\&& +\,{\beta}_{6}{\rm{LoF}}:{\rm{sex}}+{\beta}_{7}{\rm{LoF}}:{\rm{age}}+{\beta}_{8}{\rm{sex}}:{\rm{age}}+{\beta}_{9}{\rm{age}}^{2}\\ &&+\,{\beta}_{10}{\rm{site}} +\,{\beta}_{11}{\rm{trauma}}/{\rm{Townsend}}\,{\rm{index}}\\...
Argentina Últimas Noticias, Argentina Titulares
Similar News:También puedes leer noticias similares a ésta que hemos recopilado de otras fuentes de noticias.
Sunday Funday: 904 Pop Up hosts 200 vendors, 15 food trucks to support local businessesHaving fun in the sun | Vendors of all kinds can be found at the 904 Pop Up event this Sunday!
Leer más »
ATEEZ Scores Their 1st Top 2 Entry On Billboard 200 With “THE WORLD EP.2 : OUTLAW”ATEEZ Scores Their 1st Top 2 Entry On Billboard 200 With 'THE WORLD EP.2 : OUTLAW' 2_BB200_ATEEZ
Leer más »
Couple charged after nearly 200 goats were found dead on their farmIn addition to the deceased goats found at the farm, investigators believe that the couple have sold about 265 goats from Dec. 2020 and March 2023.
Leer más »
200 straphangers evacuated as L train derails in Brooklyn | amNewYorkAbout 200 straphangers were safely evacuated after an L train partially derailed in Canarsie, Brooklyn Sunday evening.
Leer más »
More than 200 dogs line up to greet man on his 100th birthdayThis is so sweet!
Leer más »
A bit of something for everyone at Handmade Saskatchewan YXE gift storeHandmade Sask YXE offers something for everyone from almost 200 Saskatchewan-based vendors yxe
Leer más »