People who took the opioid oxycodone or a placebo for six weeks reported similar pain scores for acute discomfort in their lower back or neck
a class of painkiller that includes the drugs morphine, oxycodone and fentanyl.
Opioids can be highly addictive, which may lead to drug abuse. “There’s been a global move to readdress the appropriate use of opioids because we know they carry a significant burden of harm,” says McLachlan., but no studies had looked at acute lower-back pain or any duration of neck pain. To learn more, McLachlan and his colleagues recruited 347 people with acute lower back or neck pain between 2016 and 2021.
For up to six weeks, half of the participants were randomly assigned to take a daily dose of oxycodone and the medicine naloxone, which offsets some opioid side effects, while the other half took a placebo. The doctors also gave all of the participants typical pain management advice, such as keeping active.
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