Researchers have found that consuming THC during pregnancy can lead to genetic changes during a baby’s growth in the womb that are consistent with those seen in people with autism spectrum and attention deficit hyperactivity disorders.
July 7, 2023 – Researchers have found that consuming delta-9-tetrahydrocannabinol, or THC, during pregnancy can lead to genetic changes during a baby’s growth in the womb that are consistent with those seen in people with autism spectrum and attention deficit hyperactivity disorders., come from experiments conducted on non-human primates by researchers at Oregon Health & Science University.
“Cannabis is one of the most commonly used drugs and is widely available across the country, so there is a common perception that it’s completely safe to use,” said the study’s lead author Lyndsey Shorey-Kendrick, PhD, a computational biologist at OHSU’s Oregon National Primate Research Center, in a. “The reality is that cannabis still carries many health risks for certain populations, including those who are pregnant.
In their article, the researchers noted that previous studies have linked maternal cannabis use with an increased risk for preterm birth, stillbirth, and low birth weight. Studies in mice have shown that exposure increased anxiety and altered brain DNA in baby mice. Prior research has also shown associations between maternal cannabis use and autism spectrum disorder, ADHD, intellectual disability and learning disorders, and other neuropsychiatric disorders, they wrote.
This latest study sought to understand how THC changes genes during fetal development. Researchers gave a group of five pregnant research monkeys a daily THC edible throughout their pregnancies, and another group of five pregnant monkeys got a placebo. The monkeys gave birth by caesarean section , and tissue was sampled during the delivery from five places: the placenta, a lung, two parts of the brain, and the heart.
The primates used in the research, called rhesus macaques, have DNA that is 93% similar to that of humans, and have been used to develop some of the largest medical advances for humans in the world, including vaccines and reproductive treatments, according to summaries from
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