Many common drugs consist of chemicals sourced from crude oil, a situation that needs to change if we're to reduce our dependence on fossil fuels.
, out of a compound found in pine trees. The compound is also a waste product from the paper industry and could be a sustainable replacement for the oil chemicals., and it comes from turpentine. The researchers were also able to make several other useful chemicals from turpentine, including ones that could be developed into beta blockers, asthma drugs, and cleaning products.
"Our turpentine-based biorefinery model uses waste chemical by-products from the paper industry to produce a spectrum of valuable, sustainable chemicals that can be used in a wide range of applications from perfumes to paracetamol,"The method Tibbetts' team deployed uses what are known as, which are exactly what they sound like: chemical reactions happen continuously, rather than in batches, a little bit like a conveyor belt of chemicals.
A carefully calibrated series of reactions are required to get from β-pinene to intermediates for acetaminophen and ibuprofen, with the sort of yields that would make sense in terms of efficiency and scalability. The method needs development before it can be scaled up to a commercial level, and is likely to be more expensive than processes based on crude oil. That could all change with further refinement, and paying a little extra for now is something we might be more inclined to accept if it means protectingTaking a more long term view, fossil fuels are a limited resource. Eventually, we'll need an alternative.
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