Contrary to current conventional wisdom, patients with chronic kidney disease who develop mild or moderate acute kidney injury have only a small subsequent worsening of kidney function. CKD MedTwitter
The researchers say that many"prior studies were biased" by not factoring in the fact that patients who develop mild-to-moderate AKI already had worse pre-existing kidney function and vulnerable kidneys.
"We more rigorously controlled for these differences and conclude that the impact of mild-to-moderate AKI is actually very modest," said Hsu. "Our study is not a clinical trial so we have to be careful about making conclusions regarding causality, but given that there is no independent association between mild-to-moderate AKI and subsequent loss of kidney function it seems unlikely that preventing mild-to-moderate AKI will prevent accelerated progression of CKD," Hsu said in an interview
"Our study is compelling because we have research-grade data that no other study had and is better controlled for differences between those who did and did not get AKI."Wilson cautioned, however, that"It's important to realize even if AKI is not causally linked to worsening kidney disease, it nevertheless flags an individual at higher risk of progression.
During a median follow-up of 3.9 years, 433 of these patients had a total of 612 AKI episodes, of which 68% were deemed mild , 24% moderate , and 8% severe . After adjusting for multiple demographic and clinical criteria, including baseline estimated glomerular filtration rate , changes in eGFR from baseline following an AKI episode showed no significant relationship with AKI events.
Argentina Últimas Noticias, Argentina Titulares
Similar News:También puedes leer noticias similares a ésta que hemos recopilado de otras fuentes de noticias.
12-year-old kidney transplant recipient goes to 'medical school' through Make-A-Wish IllinoisThe experience made Melanie sure of what she wants to be when she grows up: a kidney doctor.
Leer más »
High school teacher getting ready to donate kidney to student'I could thank him for the rest of my life and it would still never be enough.' This math teacher is getting ready to donate a kidney to one of his high school students, giving more than just skills for life
Leer más »
San Diego's Travere Therapeutics to sell a piece of its liver disorder drug portfolio for $445MMirum Pharmaceuticals gets two FDA-approved drugs targeting people with rare liver and kidney disorders
Leer más »
Groundbreaking Alzheimer’s drug slows disease: A ‘new era’ for treatmentDonanemab has been linked to a 40% lower risk of progressing from mild cognitive impairment to mild dementia.
Leer más »
Meta Told to Hand Over Threads Content Moderation Documents to CongressJim Jordan is coming for Meta's new Threads app after accusing the company of colluding with the government to moderate content.
Leer más »
For a good heart workout, it's OK to wait for the weekend, new research findsGetting 150 minutes of moderate to vigorous activity a week is the goal, whether it's done in one or two days or spread out through the week.
Leer más »