Long COVID Might Ruin Booze For You

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Long COVID Might Ruin Booze For You
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“I just really, really struggled if I had one drink. I would wake up so hungover, terrible headaches, and super tired. It was so bizarre.”

“It doesn't surprise me at all because we now know there are all sorts of underlying biological abnormalities in people with ME/CFS that involve the immune system, energy metabolism, brain, autonomic nervous system, and microbiome of the gut, most of which now are showing up in people with long COVID,” said Dr. Anthony Komaroff, a professor of medicine at Harvard Medical School who has studied ME/CFS for 35 years.

The condition doesn’t go away, but people can manage it by avoiding booze of all kinds. People of Asian descent are more likely to have the genetic mutation, so they have the condition at greater rates compared with other racial groups. Both conditions can cause nausea, but an alcohol allergy is typically more painful and can be life-threatening if untreated.

It’s also possible the coronavirus may directly affect the enzymes responsible for processing alcohol, said Dr. Vikrant Rachakonda, a hepatologist, gastroenterologist, and professor of medicine at UC Davis Health. There are several plausible explanations behind post-COVID alcohol intolerance, but it has not been thoroughly studied. Most speculations are based on what scientists have learned about long COVID’s impacts on the body and research on ME/CFS.

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