Genetic analyses in a cohort of patients with melanoma receiving immunotherapy reveal that variants in IL7 are associated with immune-related adverse events, and highlight the role of Bcells in mediating toxicity fairfaxlab MRC_WIMM OxcordOncology
We are very grateful to all patients who contributed samples and participated in the study. We thank all the staff of the Day Treatment Unit, Oxford Cancer Centre and the Brodey Centre at the Horton General Hospital. We are grateful to all the staff of the Oxford University Hospitals NHS Foundation Trust haematology and biochemistry laboratory and thank T. James for his facilitation, as well as the staff of the Oxford Radcliffe Biobank and Churchill Hospital Sample Handling Lab.
Chelsea A. Taylor, Robert A. Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J. Gilchrist, Alba Verge de los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A. Cooper, Victoria K. Woodcock, Elsita Jungkurth & Benjamin P. FairfaxChelsea A. Taylor, Robert A. Watson, Orion Tong, Weiyu Ye, Isar Nassiri, Alba Verge de los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A. Cooper, Victoria K. Woodcock, Elsita Jungkurth, Mark R. Middleton & Benjamin P.
Oxford Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK Robert A. Watson, Victoria K. Woodcock, Nicholas Coupe, Miranda J. Payne, David N. Church, Mark R. Middleton & Benjamin P.
Department of Medical Oncology, Division of Population Sciences, Dana-Farber Cancer Institute, Boston, MA, USAStefan Groha, Matthew L. Freedman, Toni K. Choueiri & Alexander GusevLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UKNational Institute for Health Research Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UKLank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, MA, USAToni K. ChoueiriMark R.
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