The flesh-rotting 'zombie drug' xylazine has been wreaking havoc in the US.
The death involved a 43-year-old man with a history of illicit drug use. No natural disease was identified in any of his main organ systems by the post-mortem examination. But several drugs were detected by post-mortem toxicology: eight in both the blood and urine, and an additional three in the urine.
The man's death was concluded to have occurred from a combination of heroin, fentanyl, cocaine, and xylazine. There was evidence to suggest that this drug combination had been injected. When Dr Alexander Lawson, a toxicologist at Birmingham Heartlands Hospital and co-author of our report, analyzed the blood and urine samples for this case, he noticed an anomalous peak in the original test results, which was subsequently identified as xylazine.Xylazine is not included in standard toxicology drug screens in the UK, so its identification in this case was due to the vigilance of Dr Lawson and his team.
Most of the heroin in the UK has historically come from Afghanistan, whereas heroin in the US usually originates from central and South America. However, the Taliban appear to be holding firm to their promise toWhile the origin of the heroin used in this death in the UK has not been confirmed, this may represent a resulting shift in the UK heroin supply to central and Southern American origins.
Heroin users should therefore be made aware of the additional risks of using"tranq dope", especially as the opioid overdose reversal agent naloxone is not effective against the sedative effects of xylazine.
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