Gene therapy could help treat millions affected with glaucoma

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Gene therapy could help treat millions affected with glaucoma
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Researchers hijacked a virus to help decrease the pressure build-up in the eye.

An industry-academia partnership between Exhaura Limited and Trinity College Dublin has led to the development of gene therapy as a treatment option for glaucoma patients. An eye disorder that can lead to vision loss and blindness, glaucoma affects approximately 80 million people around the world.

. Researchers at Trinity College spent the last years working on a gene therapy that can be used against a commonly occurring disease.Glaucoma is a group of eye conditions that can eventually lead to blindness. However, the cause of vision loss in these conditions is the same, damage to the optical nerve caused by a build-up of pressure inside the eye.

, the build-up of unwanted proteins inside the eye results in the blockage of drainage channels. This leads to the accumulation of fluid inside the eye and the resultant pressure leading to damage to the head of the optical nerve.Currently, topical eye drops are used to prevent the disease from progressing in glaucoma patients. However, there is also a subset of patients who develop resistance to the treatment.

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