ECT in older patients with refractory depression & bipolar disorder has been linked to cognitive improvement. MedTwitter AAGP AAGP2023
=.023), and language index score ; a trend of an age group effect was observed with the orientation index score .
Of note, the mean changes in all cognitive and memory scores were small across all age groups, with all showing a less than 1-point increase or decrease compared with scores prior to ECT.McArdle speculated that the improvements observed among older patients may be associated with a reduction in depressive symptoms.
"Prior studies utilizing a brief assessment such as the MoCA have focused primarily on total MoCA score rather than domain index scores. Utilizing these domain index scores can provide clinicians with a slightly more granular assessment to monitor cognition throughout a course of ECT," McArdle said.
"This is very relevant for all ages, but especially important in the older adult population. The improvements, or minimal impact, in cognition in patients treated with ECT may be related more to the clinical presentation of mood disorders in the elderly, who tend to have a cognitive component. So, as the mood disorder improves, we also expect an improvement in cognition," said Pritchett.
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