CV benefit from vitamin-D caps hinted in huge D-Health trial MedicalNews
, and those taking >500 IU/day vitamin D supplements were excluded from enrollment. Participants ranged in age from 60-84 at randomization and 46% were women.
Vitamin D at moderate dosages has low toxicity, Neale said,"so I think it would be reasonable for clinicians to consider supplementing elderly people who do not have contraindications, particularly those who have underlying risk factors for CV disease," Neale said. But patients should be told that the evidence for such a recommendation is not strong, so they can make an informed decision, she added.
Also, she said, the study's authors observed a possible vitamin-D protective effect"among people who were vitamin D sufficient at baseline, but not among those who were insufficient. It is important to interpret this finding with caution because they used predicted, not measured, vitamin D status for these analyses."
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