One month after receiving a booster with the bivalent vaccine, those older than 55 had 4x more neutralizing antibodies against these Omicron subvariants compared with people who received the original monovalent vaccine as a booster in a recent study.
by the US Food and Drug Administration for ages 5 years and older. The safety and tolerability profile of the Pfizer/BioNTech bivalent booster remains favorable and similar to the original COVID-19 vaccine, the company reported.
"For example, there may be significant differences between the groups, and the release mentions at least one difference that is of importance: the interval since the last vaccination which often affects the response to subsequent boosting," she said. More researcher results are warranted."These data do not indicate that these differences between the two vaccines translate into a meaningful clinical benefit at a population level," El Sahly said."As we head into the holiday season, we hope these updated data will encourage people to seek out a COVID-19 bivalent booster as soon as they are eligible in order to maintain high levels of protection against the widely circulating Omicron BA.4 and BA.
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