Regulators must decide soon which strains to include in a fall vaccine against the ever-changing coronavirus.
should make up the next iteration of vaccine, so that the agency can greenlight a version for companies to mass-produce.
This hedging proved unwarranted: All major new variants have flowed from Omicron, which was first detected in South Africa in November 2021. And evidence increasingly shows that a vaccine split between a current strain and one that’s extinct makes it harder for people to mount a strong immune response to the virus.a preprint study of 72 people
Last week, a WHO advisory group said in a statement that although current COVID-19 vaccines guard against severe disease, “protection against symptomatic disease is limited and less durable.” In place of a bivalent shot, the groupnow dominating across continents, although it left the door open to other effective vaccine recipes.
peaked at about 30% 2 weeks after someone got the shot and fell to 0% at 16 weeks. “It’s not an unreasonable supposition” that a closer match could perform a bit better, though the effect is still unlikely to persist, Messer says.
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