All subtypes of dementia, irrespective of patients’ previous dementia types, behaved like rapidly progressive dementia following COVID-19, according to the Journal of Alzheimer’s Disease Reports Infection with SARS-CoV-2 has a significant impact on cognitive function in patients with preexisting
A study published in the Journal of Alzheimer’s Disease Reports reveals that infection with SARS-CoV-2 significantly impacts cognitive function in patients with preexisting dementia, causing rapidly progressive dementia. Researchers investigated 14 patients with various types of dementia and found that following COVID-19 infection, the differences between dementia subtypes became blurred, and cognitive deterioration progressed rapidly.
“Brain fog” is an ambiguous terminology without specific attribution to the spectrum of post-COVID-19 cognitive sequelae. Based on the progression of cognitive deficits and the association with white matter intensity changes, the authors propose a new term: “FADE-IN MEMORY.” Credit: Journal of Alzheimer Disease Reports
Co-investigator Ritwik Ghosh, MD, Department of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India, expressed his concern about dementia subtyping. “It is more difficult in the post-COVID-19 era, where the history of this viral infection plays the most important role. Few patients with a history of COVID-19 without preexisting dementia have phenotypically and imaging-wise similar brain changes mimicking other degenerative and vascular dementias.
The rapid progression of dementia, the addition of further impairments/deterioration of cognitive abilities, and the increase or new appearance of white matter lesions suggest that previously compromised brains have little defense to withstand a new insult .
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