Psychological stress is known to worsen the gut inflammation caused by certain bowel diseases. Now scientists have found out why.
Credit: Steve Gschmeissner/Science Photo Library
outlines a sweeping narrative that begins with chemical cues produced in the brain and ends with immune cells in the gut — a sequence that spells trouble for people with these conditions., helps to explain how chronic stress can trigger physical distress. And it implies that managing stress levels might have a profound influence over the effectiveness of.
At the same time, glucocorticoids block immature gut neurons from developing fully, the researchers found. As a consequence, these neurons produce only low levels of signalling molecules that cause gut muscles to contract. This means food moves slowly through the digestive system, which adds to the discomfort of IBD.
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