Chronic pain linked to distinctive patterns of brain activity

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Chronic pain linked to distinctive patterns of brain activity
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Better understanding the brain patterns linked to persistent pain could open the door to new treatments

The team implanted electrodes and stimulators into the brains of four people with chronic pain as a result of a stroke or amputation. These recorded electrical activity in the brain regions that have been associated with the potentially long-term emotional and cognitive aspects of pain – the orbitofrontal cortex and the anterior cingulate cortex – which the researchers anticipated are more involved in chronic discomfort than some other brain regions that have been linked to short-lived pain.

then linked these electrical signals to the participants’ self-reported pain severity. From this, the researchers identified neural patterns that indicated whether the individual was experiencing a high or low pain state, acting as a biomarker for different levels of discomfort.Get the most essential health and fitness news in your inbox every Saturday.

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