AxSpA-IBD: AxSpA Remission on TNFi Seen in Half of Patients

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AxSpA-IBD: AxSpA Remission on TNFi Seen in Half of Patients
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About half of patients living with both axial spondyloarthritis and IBD reached clinical remission of axSpA at 12 months after starting a tumor necrosis factor inhibitor, researchers have found.

CLEVELAND – About half of patients living with both axial spondyloarthritis and inflammatory bowel disease reached clinical remission of axSpA at 12 months after starting a tumor necrosis factor inhibitor , researchers have found.

He presented the results at the annual meeting of the Spondyloarthritis Research and Treatment Network .Included in the retrospective cohort study were 82 adults with IBD and either ankylosing spondylitis or sacroiliitis who started anti-TNF agents approved for IBD between January 2012 and October 2021 at a large academic center.

"Some patients had good response to anti-TNF treatments for their IBD but not necessarily for their spondyloarthritis," he explained. "We don't have much data to tell us who's going to respond to treatments from both diseases simultaneously," he said.Jean Liew, MD, a spondyloarthritis specialist at Boston University, who was not part of the study, noted that the team reported univariate associations of clinical factors with achievement of clinical axSpA remission, but no multivariable analyses with adjustment for potential confounders.

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