THIS JUST IN: To date, nine children less than 10 years old have been identified as positive for adenovirus and two have required liver transplants.
The affected children were from throughout the state of Alabama, and an epidemiological linkage among them has not been determined.
None of these children has had any underlying health conditions of note. ADPH issued a Health Alert Network notification on February 1, 2022, to elicit additional cases, and ADPH is updating the HAN for redistribution. ADPH continues to collaborate with the CDC. Other entities working with ADPH include Children’s of Alabama and Texas Children’s. New York State Health Department Wadsworth Center and the Infectious Disease Pathology Branch at CDC have been performing the testing on the specimens in these cases.
CDC is developing a national Health Advisory looking for clinically similar cases with liver injury of unknown etiology or associated with adenovirus infection in other states and is discussing similar cases of hepatitis potentially associated with adenovirus with international colleagues. Adenoviruses are common viruses that typically cause a mild, self-limiting flu-like or gastrointestinal illness. Rarely, in otherwise healthy individuals, do these viruses cause an illness so severe that they need to be hospitalized and may die.
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