A new platelet-rich fibrin matrix is becoming a promising and affordable alternative for treating chronic diabetic ulcers (diabetic foot), a pilot study suggests.
. Their average age was 54 years, and they had chronic ulcers on the lower limbs associated with complex and difficult-to-control diabetes. Patients with ulcers of other etiologies were excluded from the study.
The ulcers did not show ischemic macroangiopathy, active infection after debridement, or limitations related to the area, depth, or type of exposed tissue. Moreover, they had previously been treated with, systemic antibiotic therapy, and photodynamic therapy, varying between two and four sessions. Until the beginning of the study, the existing PRF matrices were not viable for treating more extensive lesions, despite their action on forming membranes with good cellular quality. However, according to Furst and Correa, the product developed by the UFJF oral and maxillofacial surgery team can create aAfter the first session, the authors observed an average reduction in lesion area of 36.6%. After the second and third weeks, the average reductions were 22% and 39%, respectively.
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