The intravenous treatment showed a high success rate in preventing the parasitic disease. Find out more at 🚀
Malaria is a mosquito-borne disease that infected nearly 241 million people globally in 2020, according to the World Health Organization . It is caused Plasmodium parasites, which are transmitted when a mosquito injects the parasites in a form called sporozoites, specifically Plasmodium Falciparum parasites into the skin and bloodstream of humans. Once there, it travels to the liver, where it multiplies and spreads.
For years, scientists have been working on developing a new treatment that uses a monoclonal antibody — a laboratory-made antibody — to defuse and destroy the disease-causing insect before it can infect the body.NIAID funded the trial, which was led by Dr. Peter D. Crompton, the chief of the Malaria Infection Biology and Immunity Section in the NIAID Laboratory of Immunogenetics, and Dr. Kassoum Kayentao, professor at the University of Sciences, Techniques and Technologies of Bamako, Mali.
The first part of the study examined the safety of the three different doses of the monoclonal antibody. The doses were 5 milligrams per kilogram of body weight , 10 mg/kg and 40 mg/kg. Each dose was given intravenously.
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