A Key to Cancer Research: The Origin-of-Life Molecule

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A Key to Cancer Research: The Origin-of-Life Molecule
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Researchers from Spain and Denmark have discovered a technique for attacking cancer cells in the production of one of the origin-of-life molecules. The molecule that gave rise to life, RNA, has been demonstrated to be important for repairing human genetic material and avoiding mutations that migh

The researchers discovered that inhibiting RNA synthesis with the THZ1 compound and analogs following therapies that cause DNA breakages, such as radiation therapy, dramatically improves tumor cells’ sensitivity to death.

The research showed that following DNA-damaging treatments, such as radiation therapy, RNA synthesis inhibition with the THZ1 compound and analogs significantly increases tumor cells’ sensitivity to death. This research by the Biomedical Institute of Seville and the University of Seville, in collaboration with the Danish Cancer Society, has been published in the prestigious journal. Both researchers return to Spain from Denmark and have been able to continue their research thanks to contracts funded by the Government of Andalusia and the Spanish Association against Cancer .

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