Authorities say the two children who died were three years old and three months old.
This happened at a home just on 10th Avenue West. An 11-year-old has been taken to the hospital with serious injuries.
Authorities also say an adult woman was rescued from the home and taken to the hospital, and has been reported as conscious and talking. Officials with Birmingham Fire and Rescue say another woman is trapped inside of the home, and is talking with first responders.
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